Current Projects of Constructive Biology at Komaba Clife group

	experiment	theory	question to be addressed
construction of replicating system	replicating system in vitro with several enzaymatic reactions	replication model with few number of molecules	origin of information evolvability
cell system	replicating liposome with internal reaction network	recursive growth of autocatalytic reaction system	network for recursive growth
multicellular system	interaction-induced differentiation of an ensemble of cells	isologous diversification in inter-intra dynamics	robustness in development
developmental process	activin-controlled construction of tissues	stem cell dynamics and pattern formation	irreversibility in development/origin of positional information
generation	germ-line segregation from ensemble of cells	recursive colony with differential adhesion	ensemble recursibity/origin of individuality
memory	dynamic memory and learning in cell	memory and learning in dynamical systems	irreversible control
evolution	relevance of phenotypic differentiation in E coli evolution	symbiotic sympatric speciation	genetic fixation of phenotypic differentiation
symbiotic system	symbiosis between different organisms	joinability of dynamical systems	extensionability of system